The SAFIR study on familial hypercholesterolemia

has started

13 february 2018

Led by the Nantes University Hospital as part of the CHOPIN project, the SAFIR study, which looks at familial hypercholesterolemia, has taken on its first patients


Based on the clinical observation that many relatives of patients with familial hypercholesterolemia (FH) do not go on to develop cardiovascular complications, the SAFIR protocol focuses on the study of these patients’ phenotypes in order to identify genetic atheroprotective factors in the patients.

The SAFIR study, coordinated by the Nantes University Hospital, brings together 8 French university hospitals including the  Dijon, Lyon, Nantes, Paris, Marseille, Rennes and Toulouse University Hospitals.

With the first patient enrolled in December 2017 in Nantes, the protocol currently has 25 participants and constitutes a first step towards identifying vascular protection targets in FH patients.